|Other Names||A disintegrin and metalloproteinase with thrombospondin motifs 15, ADAM-TS 15, ADAM-TS15, ADAMTS-15, 3424-, ADAMTS15|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP9256b was selected from the C-term region of human ADAMTS15. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Expressed in fetal liver and kidney, but not in any of the adult tissues examined|
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Provided below are standard protocols that you may find useful for product applications.
ADAMTS15 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS15 family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
Viloria,C.G., et.al., Cancer Res. 69 (11), 4926-4934 (2009)Porter,S., et.al., Int. J. Cancer 118 (5), 1241-1247 (2006)
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