ADAMTS15
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC-P |
|---|---|
| Primary Accession | Q8TE58 |
| Reactivity | Human |
| Calculated MW | 103287 Da |
| Gene ID | 170689 |
|---|---|
| Dilution | IHC-P~~N/A |
| Storage | Maintain refrigerated at 2-8°C |
| Precautions | ADAMTS15 is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ADAMTS15 |
|---|---|
| Function | Metalloprotease which has proteolytic activity against the proteoglycan VCAN, cleaving it at the 'Glu-1428-|-1429-Ala' site. Cleaves VCAN in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration. |
| Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P59384}. Cell surface {ECO:0000250|UniProtKB:P59384} |
| Tissue Location | Expressed in fetal liver and kidney, but not in any of the adult tissues examined. |

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