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PLVAP Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BX97
Additional Information
Gene ID 83483
Other Names Plasmalemma vesicle-associated protein, Fenestrated endothelial-linked structure protein, Plasmalemma vesicle protein 1, PV-1, PLVAP, FELS, PV1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms FELS, PV1
Function Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development.
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q9WV78}; Single-pass type II membrane protein. Membrane, caveola {ECO:0000250|UniProtKB:Q9WV78}; Single-pass type II membrane protein. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q9WV78}. Note=Membrane-associated protein of caveolae. Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels. Also colocalized with CAV1 in perinuclear region. {ECO:0000250|UniProtKB:Q9WV78}
Tissue Location Expressed in lung, kidney, heart, aorta, placenta, muscle, pituitary gland, adrenals, mammary gland, bladder, lymph node, bone marrow, trachea, digestive tract, liver and tumor-associated endothelium.
Research Areas
Citations (0)

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PLVAP involved in the formation of stomatal and fenestral diaphragms of caveolae. This protein may function in microvascular permeability.


Keuschnigg, J., et al. Blood 114(2):478-484(2009)Carson-Walter, E.B., et al. Clin. Cancer Res. 11(21):7643-7650(2005)Strickland, L.A., et al. J. Pathol. 206(4):466-475(2005)Stan, R.V., et al. Mol. Biol. Cell 15(8):3615-3630(2004)Hnasko, R., et al. J. Endocrinol. 175(3):649-661(2002)Stan, R.V., et al. Genomics 72(3):304-313(2001)Stan, R.V., et al. J. Cell Biol. 145(6):1189-1198(1999)

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$ 277.78
Cat# BP9378c
Availability: 2 weeks
Bulk Size

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