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ACAD8 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UKU7
Additional Information
Gene ID 27034
Other Names Isobutyryl-CoA dehydrogenase, mitochondrial, 1399-, Activator-recruited cofactor 42 kDa component, ARC42, Acyl-CoA dehydrogenase family member 8, ACAD-8, ACAD8, ARC42, IBD
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACAD8
Synonyms ARC42, IBD
Function Isobutyryl-CoA dehydrogenase which catalyzes one of the steps of the valine catabolic pathway (PubMed:11013134, PubMed:12359132, PubMed:16857760). To a lesser extent, is also able to catalyze the oxidation of (2S)-2-methylbutanoyl-CoA (PubMed:11013134, PubMed:12359132).
Cellular Location Mitochondrion
Tissue Location Detected at comparable levels in all tissues examined (heart, lung, brain, skeletal muscle, pancreas and placenta) Weakly expressed in liver and kidney
Research Areas
Citations (0)

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Background

ACAD8 is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. This protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine.

References

Wollmer, M.A., et al. Neurogenetics 8(3):179-188(2007)Ma, J., et al. Atherosclerosis 191(1):63-72(2007)Battaile, K.P., et al. J. Biol. Chem. 279(16):16526-16534(2004)

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$ 277.78
Cat# BP9488c
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