|Other Names||Methionine adenosyltransferase 2 subunit beta, Methionine adenosyltransferase II beta, MAT II beta, Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase, MAT2B, TGR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine (PubMed:10644686, PubMed:23189196, PubMed:25075345). Can bind NADP (in vitro) (PubMed:23189196, PubMed:23425511).|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
MAT2B belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT.
Martinez, C.A., et al. Am. J. Obstet. Gynecol. 201 (4), 394 (2009) : Boyles, A.L., et al. Genet. Epidemiol. 33(3):247-255(2009) Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) : Attia, R.R., et al. J. Biol. Chem. 283(45):30788-30795(2008) Wang, Q., et al. World J. Gastroenterol. 14(29):4633-4642(2008) LeGros, L., et al. J. Biol. Chem. 276(27):24918-24924(2001)
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