|Application ||IHC-P, WB, E|
|Calculated MW||37552 Da|
|Antigen Region||80-107 aa|
|Other Names||Methionine adenosyltransferase 2 subunit beta, Methionine adenosyltransferase II beta, MAT II beta, Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase, MAT2B, TGR|
|Target/Specificity||This MAT2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-107 amino acids from the N-terminal region of human MAT2B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MAT2B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine (PubMed:10644686, PubMed:23189196, PubMed:25075345). Can bind NADP (in vitro) (PubMed:23189196, PubMed:23425511).|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
MAT2B belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT.
Martinez, C.A., et al. Am. J. Obstet. Gynecol. 201 (4), 394 (2009) :
Boyles, A.L., et al. Genet. Epidemiol. 33(3):247-255(2009)
Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :
Attia, R.R., et al. J. Biol. Chem. 283(45):30788-30795(2008)
Wang, Q., et al. World J. Gastroenterol. 14(29):4633-4642(2008)
LeGros, L., et al. J. Biol. Chem. 276(27):24918-24924(2001)
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