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SACM1L Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NTJ5
Additional Information
Gene ID 22908
Other Names Phosphatidylinositide phosphatase SAC1, 313-, Suppressor of actin mutations 1-like protein, SACM1L, KIAA0851
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Phosphoinositide phosphatase which catalyzes the hydrolysis of phosphatidylinositol 4-phosphate (PtdIns(4)P) (PubMed:24209621, PubMed:27044890, PubMed:29461204, PubMed:30659099). Can also catalyze the hydrolysis of phosphatidylinositol 3-phosphate (PtdIns(3)P) and has low activity towards phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). Shows a very robust PtdIns(4)P phosphatase activity when it binds PtdIns(4)P in a 'cis' configuration in the cellular environment, with much less activity seen when it binds PtdIns(4)P in 'trans' configuration (PubMed:29461204, PubMed:24209621, PubMed:30659099). PtdIns(4)P phosphatase activity (when it binds PtdIns(4)P in 'trans' configuration) is enhanced in the presence of PLEKHA3 (PubMed:30659099).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane. Note=Trafficking between the ER and Golgi is regulated by nutrient status and by TMEM39A (PubMed:31806350) Localizes to endoplasmic reticulum-plasma membrane contact sites (EPCS) in the presence of phosphatidylinositol-4,5-bisphosphate (PubMed:27044890).
Tissue Location Detected in heart, brain, lung, liver, kidney, pancreas and testis.
Research Areas
Citations (0)

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Phosphoinositide phosphatase that hydrolyzes PtdIns(3)P and PtdIns(4)P. Has low activity towards PtdIns(3,5)P2 (By similarity).


??iu, Y., et al. Mol. Biol. Cell 19(7):3080-3096(2008)??ohde, H.M., et al. J. Biol. Chem. 278(52):52689-52699(2003)??hong, R., et al. Plant Physiol. 132(2):544-555(2003)??iss, H., et al. Genomics 73(1):10-19(2001)

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$ 277.78
Cat# BP9560b
Availability: 2 weeks
Bulk Size

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