IL-19, human recombinant protein
Melanoma differentiation association like protein, MDA1, NG.1, ZMDA1, IL-10C, IL-19
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UHD0 |
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Calculated MW | 17.9 kDa |
Gene ID | 29949 |
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Gene Symbol | IL19 |
Other Names | Melanoma differentiation association like protein, MDA1, NG.1, ZMDA1, IL-10C, IL-19 |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥98% |
Assay2&Purity2 | HPLC; ≥98% |
Recombinant | Yes |
Target/Specificity | IL-19 |
Application Notes | Reconstitute in H₂O to a concentration of 0.1 to 1.0 µg/ µl. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum. |
Format | Lyophilized protein |
Storage | -20°C; Sterile filtered and lyophilized from 10 mM Sodium Citrate, pH 5.0 |
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Provided below are standard protocols that you may find useful for product applications.
Background
Interleukin-19 (IL-19) is a member of the IL-10 family produced by resting B cells and monocytes. IL-19 is thought to be up-regulated when monocytes are treated with GM-CSF or LPS. IL-19 shares a receptor complex with IL-20, and acts to induce IL-6 and TNF-α production by monocytes and promotes the Th2 response. Recombinant human IL-19 is a nonglycosylated protein, containing 155 amino acids, with a molecular weight of 17.9 kDa.
References
Gallagher G.,et al.Genes Immun. 1:442-450(2000).
Liao Y.-C.,et al.J. Immunol. 169:4288-4297(2002).
Wang P.,et al.BMC Genomics 10:518-518(2009).
Conklin D.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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