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> home > Products > Primary Antibodies > Signal Transduction > Anti-PCK-26 Antibody (Monoclonal, PCK-26)
Anti-PCK-26 Antibody (Monoclonal, PCK-26)
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Application 
| WB, IHC-P, IHC-F |
|---|---|
| Primary Accession | Q10758 |
| Host | Mouse |
| Isotype | Mouse IgG1 |
| Reactivity | Human, Mouse, Rat |
| Clonality | Monoclonal |
| Format | Lyophilized |
| Description | Mouse IgG monoclonal antibody for PCK-26 detection. Tested with WB, IHC-P, IHC-F in Human;mouse;rat. No cross reactivity with other proteins. |
| Reconstitution | Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
| Gene ID | 25626 |
|---|---|
| Other Names | Keratin, type II cytoskeletal 8, Cytokeratin endo A, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8, Krt8, Krt2-8 |
| Calculated MW | 54019 MW KDa |
| Application Details | Immunohistochemistry(Paraffin-embedded Section), 1-2 µg/ml, Human, mouse, rat, By Heat Immunohistochemistry(Frozen Section), 1-2 µg/ml, Human, mouse, rat, - Western blot, 0.5-1 µg/ml, Human, mouse, rat |
| Subcellular Localization | Cytoplasm . Nucleus, nucleoplasm . Nucleus matrix . |
| Tissue Specificity | Expressed in cardiac and striated muscle. Expressed at Z-lines within the muscle fibers and at Z-line and M- line domains at costameres at the sarcolemmal membrane (at protein level). Observed in coagulating gland, bladder, salivary gland, kidney, spleen, thymus, lung and heart. Also observed in ventral prostate, seminal vesicle and liver where expression increases following castration. . |
| Protein Name | Keratin, type II cytoskeletal 5 |
| Contents | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. |
| Clone Names | PCK-26 |
| Immunogen | Cytokeratin from human epidermis. |
| Purification | Ascites |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Belongs to the intermediate filament family. |
| Name | Krt8 |
|---|---|
| Synonyms | Krt2-8 |
| Function | Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
| Cellular Location | Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix |
| Tissue Location | Expressed in cardiac and striated muscle. Expressed at Z-lines within the muscle fibers and at Z-line and M-line domains at costameres at the sarcolemmal membrane (at protein level). Observed in coagulating gland, bladder, salivary gland, kidney, spleen, thymus, lung and heart. Also observed in ventral prostate, seminal vesicle and liver where expression increases following castration |
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin(mixture) is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues.
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$ 370.00
Cat# ABO10467
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