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> home > Products > Primary Antibodies > Signal Transduction > Anti-DSG1/Desmoglein 1 Rabbit Monoclonal Antibody
Anti-DSG1/Desmoglein 1 Rabbit Monoclonal Antibody
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Application 
| WB, IHC, IF, ICC |
|---|---|
| Primary Accession | Q02413 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-DSG1/Desmoglein 1 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 1828 |
|---|---|
| Other Names | Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, DG1, DGI, Pemphigus foliaceus antigen, DSG1, CDHF4 |
| Calculated MW | 113748 MW KDa |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 |
| Subcellular Localization | Cell membrane ; Single-pass type I membrane protein. Cell junction, desmosome. |
| Tissue Specificity | Epidermis, tongue, tonsil and esophagus. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: ED-4 |
| Immunogen | A synthesized peptide derived from human DSG1 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | DSG1 |
|---|---|
| Synonyms | CDHF4 |
| Function | Component of intercellular desmosome junctions (PubMed:34368962). Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion (PubMed:19717567). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q7TSF1} Cell junction, desmosome. Cytoplasm. Nucleus |
| Tissue Location | Expressed in all suprabasal layers of the epidermis, with the highest expression seen in the granular layer (at protein level). |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13292
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