Anti-SOX11 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IF, ICC, IP |
|---|---|
| Primary Accession | P35716 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-SOX11 Rabbit Monoclonal Antibody . Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 6664 |
|---|---|
| Other Names | Transcription factor SOX-11, SOX11 |
| Calculated MW | 46679 MW KDa |
| Application Details | WB 1:1000-1:2000 ICC/IF 1:50-1:200 IP 1:50 |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed mainly in the nervous system, brain (fetus and adult) and hear (adult).. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: GIO-19 |
| Immunogen | A synthesized peptide derived from human SOX11 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | SOX11 |
|---|---|
| Function | Transcription factor that acts as a transcriptional activator (PubMed:24886874, PubMed:26543203). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron (By similarity). Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267, ECO:0000269|PubMed:24886874, ECO:0000269|PubMed:35938035} |
| Tissue Location | Expressed primarily in the brain and heart, with low expression in the kidney, pancreas and muscle |

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