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> home > Products > Primary Antibodies > Signal Transduction > Anti-VAMP2 Rabbit Monoclonal Antibody
Anti-VAMP2 Rabbit Monoclonal Antibody
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Application 
| WB, IF, ICC, IP, FC |
|---|---|
| Primary Accession | P63027 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-VAMP2 Rabbit Monoclonal Antibody . Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 6844 |
|---|---|
| Other Names | Vesicle-associated membrane protein 2, VAMP-2, Synaptobrevin-2, VAMP2 (HGNC:12643), SYB2 |
| Calculated MW | 12663 MW KDa |
| Application Details | WB 1:1000-1:5000 ICC/IF 1:50-1:200 IP 1:50 FC 1:50 |
| Subcellular Localization | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Cell membrane. Neuronal synaptic vesicles. Colocalizes with PRKCZ and WDFY2 in intracellular vesicles (PubMed:17313651).. |
| Tissue Specificity | Nervous system and skeletal muscle.. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: AAEG-22 |
| Immunogen | A synthesized peptide derived from human VAMP2 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | VAMP2 (HGNC:12643) |
|---|---|
| Synonyms | SYB2 |
| Function | Involved in the targeting and/or fusion of transport vesicles to their target membrane (By similarity). Major SNARE protein of synaptic vesicles which mediates fusion of synaptic vesicles to release neurotransmitters. Essential for fast vesicular exocytosis and activity-dependent neurotransmitter release as well as fast endocytosis that mediates rapid reuse of synaptic vesicles (By similarity) (PubMed:30929742). Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell membrane {ECO:0000250|UniProtKB:P63045}. Note=Colocalizes with PRKCZ and WDFY2 in intracellular vesicles (PubMed:17313651) |
| Tissue Location | Nervous system and skeletal muscle. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13769
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