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> home > Products > Primary Antibodies > Signal Transduction > Anti-EAAT2/GLT-1/SLC1A2 Rabbit Monoclonal Antibody
Anti-EAAT2/GLT-1/SLC1A2 Rabbit Monoclonal Antibody
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Application 
| WB, IP |
|---|---|
| Primary Accession | P43004 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-EAAT2/GLT-1/SLC1A2 Rabbit Monoclonal Antibody . Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 6506 |
|---|---|
| Other Names | Excitatory amino acid transporter 2, Glutamate/aspartate transporter II, Sodium-dependent glutamate/aspartate transporter 2, Solute carrier family 1 member 2, SLC1A2 (HGNC:10940) |
| Calculated MW | 62104 MW KDa |
| Application Details | WB 1:500-1:2000 IP 1:50 |
| Subcellular Localization | Membrane; Multi-pass membrane protein. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: ABED-19 |
| Immunogen | A synthesized peptide derived from human EAAT2 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | SLC1A2 (HGNC:10940) |
|---|---|
| Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:14506254, PubMed:15265858, PubMed:26690923, PubMed:7521911). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:14506254). Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:14506254). Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO13795
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