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> home > Products > Primary Antibodies > Neuroscience > Anti-Dopamine Transporter SLC6A3 Rabbit Monoclonal Antibody
Anti-Dopamine Transporter SLC6A3 Rabbit Monoclonal Antibody
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Application 
| WB, IP, FC |
|---|---|
| Primary Accession | Q01959 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Dopamine Transporter SLC6A3 Rabbit Monoclonal Antibody . Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human. |
| Gene ID | 6531 |
|---|---|
| Other Names | Sodium-dependent dopamine transporter, DA transporter, DAT, Solute carrier family 6 member 3, SLC6A3, DAT1 |
| Calculated MW | 68495 MW KDa |
| Application Details | WB 1:1000-1:5000 IP 1:50 FC 1:50 |
| Subcellular Localization | Cell membrane ; Multi- pass membrane protein. |
| Tissue Specificity | Highly expressed in substantia nigra.. |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: AACF-19 |
| Immunogen | A synthesized peptide derived from human Dopamine Transporter |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | SLC6A3 |
|---|---|
| Synonyms | DAT1 |
| Function | Mediates sodium- and chloride-dependent transport of dopamine (PubMed:10375632, PubMed:11093780, PubMed:1406597, PubMed:15505207, PubMed:19478460, PubMed:39112701, PubMed:39112703, PubMed:39112705, PubMed:8302271). Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (By similarity). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Cell projection, neuron projection {ECO:0000250|UniProtKB:P23977}. Cell projection, axon. Note=Localizes to neurite tips in neuronal cells (By similarity). Colocalizes with SEPTIN4 at axon terminals, especially at the varicosities (By similarity). {ECO:0000250|UniProtKB:P23977, ECO:0000250|UniProtKB:Q61327} |
| Tissue Location | Highly expressed in substantia nigra (PubMed:7637582). Expressed in axonal varicosities in dopaminergic nerve terminals (at protein level) (PubMed:17296554). Expressed in the striatum (at protein level) (PubMed:17296554) |
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$ 370.00
Cat# ABO14279
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