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Anti-RANK Rabbit Monoclonal Antibody

     
  • WB - Anti-RANK Rabbit Monoclonal Antibody ABO15405
    Western blot analysis of RANK expression in Human fetal liver lysate.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9Y6Q6
Host Rabbit
Isotype IgG
Reactivity Human
Clonality Monoclonal
Format Liquid
Description Anti-RANK Rabbit Monoclonal Antibody . Tested in WB application. This antibody reacts with Human.
Additional Information
Gene ID 8792
Other Names Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, ODFR, Receptor activator of NF-KB, CD265, TNFRSF11A, RANK
Calculated MW 66034 Da
Application Details WB 1:500-1:2000
Contents Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clone Names Clone: 19T81
Immunogen A synthesized peptide derived from human RANK
Purification Affinity-chromatography
Storage Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Information
Name TNFRSF11A
Synonyms RANK
Function Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL- mediated osteoclastogenesis (PubMed:9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity).
Cellular Location [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Membrane raft {ECO:0000250|UniProtKB:O35305}
Tissue Location Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland
Research Areas
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$ 370.00
Cat# ABO15405
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