Anti-RANK Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | Q9Y6Q6 |
Host | Rabbit |
Isotype | IgG |
Reactivity | Human |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-RANK Rabbit Monoclonal Antibody . Tested in WB application. This antibody reacts with Human. |
Gene ID | 8792 |
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Other Names | Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, ODFR, Receptor activator of NF-KB, CD265, TNFRSF11A, RANK |
Calculated MW | 66034 Da |
Application Details | WB 1:500-1:2000 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 19T81 |
Immunogen | A synthesized peptide derived from human RANK |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | TNFRSF11A |
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Synonyms | RANK |
Function | Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL- mediated osteoclastogenesis (PubMed:9878548). Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity). Involved in the regulation of interactions between T-cells and dendritic cells (By similarity). |
Cellular Location | [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Membrane raft {ECO:0000250|UniProtKB:O35305} |
Tissue Location | Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland |

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