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> home > Products > Primary Antibodies > Signal Transduction > Anti-PDE2A Rabbit Monoclonal Antibody
Anti-PDE2A Rabbit Monoclonal Antibody
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Application 
| WB |
|---|---|
| Primary Accession | O00408 |
| Host | Rabbit |
| Isotype | IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-PDE2A Rabbit Monoclonal Antibody . Tested in WB application. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 5138 |
|---|---|
| Other Names | cGMP-dependent 3', 5'-cyclic phosphodiesterase, 3.1.4.17, Cyclic GMP-stimulated phosphodiesterase, CGS-PDE, cGSPDE, PDE2A (HGNC:8777) |
| Calculated MW | 106 kDa |
| Application Details | WB 1:500-1:2000 |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: 26P22 |
| Immunogen | A synthesized peptide derived from human PDE2A |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | PDE2A (HGNC:8777) |
|---|---|
| Function | cGMP-activated cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:15938621, PubMed:29392776, PubMed:9210593). Has a higher efficiency with cGMP compared to cAMP (PubMed:15938621). Plays a role in cell growth and migration (PubMed:24705027). |
| Cellular Location | [Isoform PDE2A3]: Cell membrane; Lipid- anchor [Isoform PDE2A1]: Cytoplasm |
| Tissue Location | Widely expressed (PubMed:29392776, PubMed:9210593). Expressed in brain, with high expression observed in the corpus striatum (PubMed:29392776). Also expressed in heart, placenta, lung, skeletal muscle, kidney and pancreas (PubMed:29392776, PubMed:9210593) |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO16043
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