Anti-LAP3 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC |
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Primary Accession | P28838 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Human |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-LAP3 Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human. |
Gene ID | 51056 |
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Other Names | Cytosol aminopeptidase, 3.4.11.1, Prolyl aminopeptidase, LAP3 (HGNC:18449) |
Calculated MW | 56166 Da |
Application Details | WB 1:500-1:2000 IHC 1:50-1:200 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 31L65 |
Immunogen | A synthesized peptide derived from human LAP3 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | LAP3 (HGNC:18449) |
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Function | Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S- conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q68FS4}. |

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