ILP-2 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q96P09 |
Other Accession | AAK81892 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 27089 Da |
Application & Usage | Western blotting (0.5-4 µg/ml). However, the optimal dilution conditions should be determined individually. The affinity-purified rabbit antibody recognizes ~32 kDa ILP-2 in samples from human, mouse and rat origins. |
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Other Names | BIRC8 , BIRC 8, BIRC-8, ILP2, hILP2, ILP-2, hILP 2 , IAP like protein 2 |
Target/Specificity | ILP-2 |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-ILP-2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | ILP-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BIRC8 |
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Synonyms | ILP2 |
Function | Protects against apoptosis mediated by BAX. |
Cellular Location | Cytoplasm. |
Tissue Location | Testis specific in normal tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ILP-2 (for IAP-like protein-2) is a novel member of in the IAP (Inhibitor of Apoptosis) protein family. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibit apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9.
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