MDC Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | O88430.1 |
Other Accession | AAD50547 |
Reactivity | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Application & Usage | Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Rat spleen tissue lysate can be used as a positive control. |
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Other Names | Macrophage-derived chemokine, C-C motif chemokine 22, Stimulated T-cell chemotactic protein 1, CC chemokine STCP-1 |
Target/Specificity | MDC |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-mouse MDC polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | MDC Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
MDC (macrophage-derived chemokine) is a 69-amino acid CC chemokine with a N-terminal sequence of 24 residues as a signal sequence. It was originally cloned from human monocyte-derived macrophages. Recombinant MDC attracts monocyte-derived dendritic cells, activated lymphocytes and natural killer cells. MDC has anti-HIV-1 activity. Expression of MDC mRNA in macrophages is enhanced by LPS, IL-1β and TNFα. MDC is a functional ligand for CCR4.
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