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CTGF Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P29279 |
| Other Accession | BAG52518 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 38091 Da |
| Gene ID | 1490 |
|---|---|
| Application & Usage | Western blotting (0.5-4 µg/ml). Per researchers feedback, it also works well in Immunohistochemistry (10-20 µg/ml, frozen and paraffin sections). However, the optimal conditions should be determined individually. |
| Other Names | connective tissue growth factor, CCN2 , CCN-2, CCN 2, Hypertrophic chondrocyte-specific protein 24 |
| Target/Specificity | CTGF |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-CTGF polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | CTGF Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CCN2 (HGNC:2500) |
|---|---|
| Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor- induced DNA synthesis. |
| Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P29268}. Secreted {ECO:0000250|UniProtKB:P29268} |
| Tissue Location | Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
CTGF (connective tissue growth factor) is a cysteine-rich, secreted peptide. It is a new member of the peptide family that includes serum-induced immediate early gene products, a v-src-induced peptide, and a putative proto-oncogene. Among the many functions of the CTGF gene family are embryogenesis, wound healing, and regulation of extracellular matrix production.
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