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IL-21R Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9HBE5 |
| Other Accession | NP_068570 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 59130 Da |
| Gene ID | 50615 |
|---|---|
| Application & Usage | Western blot analysis (1 µg/ml). However, the optimal conditions should be determined individually. Human A431 cell lysates can be used as a positive control and an approximately 60 kDa band should be detected. |
| Other Names | IL-21, IL21R, IL 21R, Interluekin-21R, Interleukin 21R, interluekin21R |
| Target/Specificity | IL-21R |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) affinity-purified rabbit anti-human IL-21R polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | IL-21R Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IL21R |
|---|---|
| Synonyms | NILR |
| Function | This is a receptor for interleukin-21. |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Location | Selectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
IL-21 is a novel cytokine that was recently identified in human and mouse. It has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel interleukin receptor) is a new member of the class I cytokine receptor family. IL-021R forms a complex with the common cytokine receptor g chain and mediates IL-21 signaling. IL-21 and its receptor activates JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, HL-60, and THP-1 cell lines. IL-21 plays an important role in the proliferation and maturation of NK, B and T cell populations.
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