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RELM-alpha Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9EP95 |
| Other Accession | NP_065255 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 11936 Da |
| Gene ID | 57262 |
|---|---|
| Application & Usage | Western blot analysis (0.5-4 µg/ml). Recombinant murine RELMα can be used as a positive control. However, the optimal conditions should be determined individually. |
| Other Names | Resistin-like alpha, Cysteine-rich secreted protein FIZZ1 |
| Target/Specificity | RELM-alpha |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti- murine RELMα polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | RELM-alpha Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Retnla |
|---|---|
| Synonyms | Fizz1, Himf, Pmng1 |
| Function | Probable hormone. Plays a role in pulmonary vascular remodeling. |
| Cellular Location | Secreted. |
| Tissue Location | Highest levels in adipose tissue. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-alpha are still unknown. Murine RELM-alpha is a 10.0 kDa monomeric protein containing 88 amino acid residues.
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