MCP-1 Antibody
Purified Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | P13500 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 11025 Da |
Gene ID | 6347 |
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Other Names | MCP1, MCP-1, MCP 1, monocyte chemoattracctant protein-1, monocyte chemoattracctant protein 1, monocyte chemoattracctant protein |
Target/Specificity | MCP-1/MCAF |
Formulation | 100 µg (0.5 mg/ml) rabbit anti-human MCP-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Background Descriptions | |
Precautions | MCP-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CCL2 |
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Synonyms | MCP1, SCYA2 |
Function | Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:10529171, PubMed:10587439, PubMed:9837883). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:10587439, PubMed:9837883). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (PubMed:8195247, PubMed:8627182, PubMed:9792674). May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis (PubMed:8107690). |
Cellular Location | Secreted |
Tissue Location | Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level) (PubMed:23765988). Expressed in monocytes (PubMed:2513477). |

Provided below are standard protocols that you may find useful for product applications.
Background
Human macrophage/monocyte chemotactic and activating factor (MCAF), also called human monocyte chemotactic protein-1 (MCP-1), is an 8.6 kDa protein containing 76 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue microphages.

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