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BMP-8 Polyclonal Antibody
Purified Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P34820 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | Goat IgG |
| Calculated MW | 44768 Da |
| Gene ID | 656 |
|---|---|
| Other Names | BMP8, BMP-8, BMP 8, bone morphogenetic protein 8 |
| Target/Specificity | BMP-8 |
| Formulation | 100 mg (0.5 mg/ml) antigen affinity purified goat anti-BMP-8 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol and 0.02% Thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Background Descriptions | |
| Precautions | BMP-8 Polyclonal Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BMP8B |
|---|---|
| Synonyms | BMP8 |
| Function | Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). |
| Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.
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