Resistin Antibody
Purified Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
---|---|
Primary Accession | Q9HD89 |
Other Accession | NP_065148 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 11419 Da |
Gene ID | 56729 |
---|---|
Other Names | RETN, RETN1, ADSF, Adipocyte Secreted Factor , FIZZ3, FIZZ 3 |
Target/Specificity | Resistin |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-human Resistin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Background Descriptions | |
Precautions | Resistin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RETN |
---|---|
Synonyms | FIZZ3, HXCP1, RSTN |
Function | Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells (By similarity). Potentially links obesity to diabetes (By similarity). Promotes chemotaxis in myeloid cells (PubMed:15064728). |
Cellular Location | Secreted {ECO:0000250|UniProtKB:Q99P87}. |
Tissue Location | Expressed in white adipose tissue (at protein level) (PubMed:11201732). Widely expressed, with particularly strong expression in lung, bone marrow, breast and peripheral blood (PubMed:15248836). Expressed strongly in bone marrow and at lower levels in lung, but not detected in other tissues (PubMed:15064728) Isoform 2 is detected in adipose tissue, bone marrow, brain, lung, peripheral blood, placenta and thymus (PubMed:15248836) |

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Provided below are standard protocols that you may find useful for product applications.
Background
Resistin (also called adipose tissue-specific secretory factor, ADSF) is a member of the family of adipocyte secreted proteins. Resistin appears to act on skeletal muscle myocytes, hepatocytes, and adipocytes themselves, where it is s µggested to reduce insulin sensitivity leading to type 2 diabetes.

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