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Anti-DsbA Antibody (1A2-D4-G10)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P0AEG4 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2b |
| Clone Names | 1A2-D4-G10 |
| Calculated MW | 23105 Da |
| Gene ID | 75204338;948353 |
|---|---|
| Application & Usage | WB: AKT1, AKT2, AKT3 and DSBA recombinant antigen |
| Other Names | Thiol:disulfide interchange protein DsbA, dsbA, dsf, ppfA |
| Target/Specificity | Thiol:disulfide interchange protein DsbA |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | In buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Anti-DsbA Antibody (1A2-D4-G10) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | dsbA |
|---|---|
| Synonyms | dsf, ppfA |
| Function | Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. Required for pilus biogenesis. PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. |
| Cellular Location | Periplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. Required for pilus biogenesis. PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.
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