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CD74

Rabbit Monoclonal antibody(Mab)

     
  • IHC-P - CD74 AD80044-010
    Tonsil
    detail
  • IHC - CD74 AD80044-010
    Immunohistochemical analysis of paraffin-embedded human tonsil tissue using AD80044 performed on the Abcarta® FAIP-30 Fully automated IHC platform.Tissue was fixed with formaldehyde at room temperature, antigen retrieval was by heat mediation with a Citrate buffer (pH6. 0).Samples were incubated with primary antibody(Ready-to-use) for 15 min at room temperature. AmpSeeTM Detection Systems(Abcepta:AR005) was used as the secondary antibody.
    detail
  • SPECIFICATION
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Product info
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P04233
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names 318B3B6
Calculated MW 33516 Da
Additional info
Gene ID 972
Gene Name CD74
Other Names HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain, Ii, CD74, Class-II-associated invariant chain peptide, CLIP, CD74 (HGNC:1697), DHLAG
Dilution IHC-P~~Ready-to-use
IHC~~Ready-to-use
Storage This product is stored at 2-90 ℃, please use it within the expiration date.
Precautions CD74 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD74 (HGNC:1697)
Synonyms DHLAG
Function Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Cellular Location Cell membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane. Golgi apparatus, trans-Golgi network. Endosome Lysosome. Note=Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane
Research Areas
Citations (0)
citation

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$ 127.00
$ 153.00
$ 182.00
Cat# AD80044-010
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