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DOG1
Rabbit Monoclonal antibody(Mab)
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- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q5XXA6 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone Names | 759B8C7 |
| Calculated MW | 114078 Da |
| Gene ID | 55107 |
|---|---|
| Gene Name | ANO1 |
| Other Names | Anoctamin-1, Discovered on gastrointestinal stromal tumors protein 1, Oral cancer overexpressed protein 2, Transmembrane protein 16A, Tumor-amplified and overexpressed sequence 2, ANO1 |
| Dilution | IHC-P~~Ready-to-use IHC~~Ready-to-use |
| Storage | This product is stored at 2-124 ℃, please use it within the expiration date. |
| Precautions | DOG1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ANO1 |
|---|---|
| Synonyms | DOG1, ORAOV2, TAOS2, TMEM16A |
| Function | Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. |
| Cellular Location | Cell membrane; Multi- pass membrane protein. Cytoplasm. Note=Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors. |
| Tissue Location | Broadly expressed with higher levels in liver, skeletal muscle and gastrointestinal muscles |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 127.00
$ 153.00
$ 234.00
Cat# AD80045-010
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