Fascin
Mouse Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC-P |
|---|---|
| Primary Accession | Q16658 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 694C7A3 |
| Calculated MW | 54530 Da |
| Gene ID | 6624 |
|---|---|
| Gene Name | FSCN1 |
| Other Names | Fascin, 55 kDa actin-bundling protein, Singed-like protein, p55, FSCN1, FAN1, HSN, SNL |
| Dilution | IHC-P~~Ready-to-use |
| Storage | Maintain refrigerated at 2-8°C |
| Precautions | Fascin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FSCN1 |
|---|---|
| Synonyms | FAN1, HSN, SNL |
| Function | Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. |
| Cellular Location | Cytoplasm, cytosol Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cell projection, filopodium. Cell projection, invadopodium. Cell projection, microvillus. Cell junction. Note=Colocalized with RUFY3 and F-actin at filipodia of the axonal growth cone. Colocalized with DBN1 and F-actin at the transitional domain of the axonal growth cone (By similarity). {ECO:0000250|UniProtKB:Q61553, ECO:0000269|PubMed:21706053} |
| Tissue Location | Ubiquitous. |

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