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Lambda Chain

Mouse Monoclonal antibody(Mab)

     
  • IHC-P - Lambda Chain AD80089-010
    Tonsil
    detail
  • IHC - Lambda Chain AD80089-010
    Immunohistochemical analysis of paraffin-embedded human tonsil tissue using AD80089 performed on the Abcarta® FAIP-30 Fully automated IHC platform.Tissue was fixed with formaldehyde at room temperature, antigen retrieval was by heat mediation with a Citrate buffer (pH6. 0).Samples were incubated with primary antibody(Ready-to-use) for 15 min at room temperature. AmpSeeTM Detection Systems(Abcepta:AR005) was used as the secondary antibody.
    detail
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Product info
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P01701
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 700F2F8
Calculated MW 12249 Da
Additional info
Gene Name IGLC1 {ECO:0000303|PubMed:11872955, ECO:0000303|Ref.6}
Other Names Immunoglobulin lambda variable 1-51 {ECO:0000303|PubMed:11872955, ECO:0000303|Ref.7}, Ig lambda chain V-I region BL2, Ig lambda chain V-I region EPS, Ig lambda chain V-I region NEW, Ig lambda chain V-I region NIG-64, IGLV1-51 {ECO:0000303|PubMed:11872955, ECO:0000303|Ref.7}
Dilution IHC-P~~Ready-to-use
IHC~~Ready-to-use
Storage This product is stored at 2-8 ℃, please use it within the expiration date.
Precautions Lambda Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IGLV1-51 {ECO:0000303|PubMed:11872955, ECO:0000303|Ref.7}
Function Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location Secreted. Cell membrane
Research Areas
Citations (0)
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$ 106.00
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$ 153.00
$ 182.00
Cat# AD80089-010
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