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Myosin Light Chain2
Rabbit Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | P10916 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone Names | 198B6C1 |
| Calculated MW | 18789 Da |
| Gene ID | 4633 |
|---|---|
| Gene Name | MYL2 (HGNC:7583) |
| Other Names | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, MLC-2, Ventricular myosin light chain 2, MYL2 (HGNC:7583) |
| Dilution | IHC-P~~Ready-to-use IHC~~Ready-to-use |
| Storage | This product is stored at 2-226 ℃, please use it within the expiration date. |
| Precautions | Myosin Light Chain2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MYL2 (HGNC:7583) |
|---|---|
| Function | Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity). |
| Cellular Location | Cytoplasm, myofibril, sarcomere, A band {ECO:0000250|UniProtKB:P08733} |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 127.00
$ 153.00
$ 182.00
Cat# AD80100-010
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