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Tryptase
Mouse Monoclonal antibody(Mab)
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- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q15661 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 668E1F9 |
| Calculated MW | 30515 Da |
| Gene ID | 7177 |
|---|---|
| Gene Name | TPSAB1 |
| Other Names | Tryptase alpha/beta-1, Tryptase-1, 3.4.21.59, Tryptase I, Tryptase alpha-1, TPSAB1, TPS1, TPS2, TPSB1 |
| Dilution | IHC-P~~Ready-to-use IHC~~Ready-to-use |
| Storage | This product is stored at 2-308 ℃, please use it within the expiration date. |
| Precautions | Tryptase Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TPSAB1 |
|---|---|
| Synonyms | TPS1, TPS2, TPSB1 |
| Function | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315). |
| Cellular Location | Secreted. Note=Released from the secretory granules upon mast cell activation. |
| Tissue Location | Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin; in these tissues, isoform 1 is predominant. Isoform 2 is expressed in aorta, spleen, and breast tumor, with highest levels in the endothelial cells of some blood vessels surrounding the aorta, as well as those surrounding the tumor and low levels, if any, in mast cells (at protein level) |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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If you have any additional inquiries please email technical services at tech@abcepta.com.
$ 127.00
$ 153.00
$ 182.00
Cat# AD80134-010
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