Anti-Thrombomodulin
Mouse Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC-P |
|---|---|
| Primary Accession | P07204 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 746E8A9 |
| Calculated MW | 60329 Da |
| Gene ID | 7056 |
|---|---|
| Gene Name | THBD |
| Other Names | Thrombomodulin, TM, Fetomodulin, CD141, THBD, THRM |
| Dilution | IHC-P~~Ready-to-use |
| Storage | Maintain refrigerated at 2-8°C |
| Precautions | Thrombomodulin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | THBD |
|---|---|
| Synonyms | THRM |
| Function | Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. |
| Cellular Location | Membrane; Single-pass type I membrane protein |
| Tissue Location | Endothelial cells are unique in synthesizing thrombomodulin |

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