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VISTA

Rabbit Monoclonal antibody(Mab)

     
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Product info
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q9H7M9
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names 957B1D3
Calculated MW 33908 Da
Additional info
Gene ID 64115
Other Names V-type immunoglobulin domain-containing suppressor of T-cell activation, Platelet receptor Gi24 {ECO:0000303|Ref.1}, Stress-induced secreted protein-1 {ECO:0000303|Ref.2}, Sisp-1 {ECO:0000303|Ref.2}, V-set domain-containing immunoregulatory receptor, VSIR (HGNC:30085)
Storage This product is stored at 2-8 ℃, please use it within the expiration date.
Protein Information
Name VSIR (HGNC:30085)
Function Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14- mediated MMP2 activation (PubMed:20666777).
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed in spleen. Detected on a number of myeloid cells including CD11b monocytes, CD66b+ neutrophils, at low levels on CD4+ and CD8+ T-cells, and in a subset of NK cells. Not detected on B cells (at protein level). Expressed at high levels in placenta, spleen, plasma blood leukocytes, and lung. Expressed at moderate levels in lymph node, bone marrow, fat, uterus, and trachea Has low expression levels in other tissues
Research Areas
Citations (0)
citation

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$ 106.00
Cat# AD80604-010
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