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VISTA
Rabbit Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q9H7M9 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone Names | 957B1D3 |
| Calculated MW | 33908 Da |
| Gene ID | 64115 |
|---|---|
| Other Names | V-type immunoglobulin domain-containing suppressor of T-cell activation, Platelet receptor Gi24 {ECO:0000303|Ref.1}, Stress-induced secreted protein-1 {ECO:0000303|Ref.2}, Sisp-1 {ECO:0000303|Ref.2}, V-set domain-containing immunoregulatory receptor, VSIR (HGNC:30085) |
| Dilution | IHC-P~~N/A |
| Storage | Maintain refrigerated at 2-8°C |
| Name | VSIR (HGNC:30085) |
|---|---|
| Function | Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14- mediated MMP2 activation (PubMed:20666777). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in spleen. Detected on a number of myeloid cells including CD11b monocytes, CD66b+ neutrophils, at low levels on CD4+ and CD8+ T-cells, and in a subset of NK cells. Not detected on B cells (at protein level). Expressed at high levels in placenta, spleen, plasma blood leukocytes, and lung. Expressed at moderate levels in lymph node, bone marrow, fat, uterus, and trachea Has low expression levels in other tissues |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 106.00
Cat# AD80604-010
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