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Goat Anti-ERG Antibody
Peptide-affinity purified goat antibody
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- CITATIONS
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- BACKGROUND
Application 
| IHC, E |
|---|---|
| Primary Accession | P11308 |
| Other Accession | NP_001129627, 2078, 13876 (mouse), 170909 (rat) |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 100ug/200ul |
| Isotype | IgG |
| Calculated MW | 53838 Da |
| Gene ID | 2078 |
|---|---|
| Other Names | Transcriptional regulator ERG, Transforming protein ERG, ERG |
| Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-ERG Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ERG |
|---|---|
| Function | Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237, ECO:0000269|PubMed:17289661}. Cytoplasm Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Fluorescence-tracking of activation gating in human ERG channels reveals rapid S4 movement and slow pore opening. Es-Salah-Lamoureux Z, et al. PLoS One, 2010 May 28. PMID 20526358.
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Yu J, et al. Cancer Cell, 2010 May 18. PMID 20478527.
Association of SPINK1 expression and TMPRSS2:ERG fusion with prognosis in endocrine-treated prostate cancer. Leinonen KA, et al. Clin Cancer Res, 2010 May 15. PMID 20442300.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trial. Le Deley MC, et al. J Clin Oncol, 2010 Apr 20. PMID 20308673.
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