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Goat Anti-FOXQ1 / FKHRL1 Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9C009 |
| Other Accession | NP_150285, 94234, 15220 (mouse) |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 100ug/200ul |
| Isotype | IgG |
| Calculated MW | 41526 Da |
| Gene ID | 94234 |
|---|---|
| Other Names | Forkhead box protein Q1, HNF-3/forkhead-like protein 1, HFH-1, Hepatocyte nuclear factor 3 forkhead homolog 1, FOXQ1, HFH1 |
| Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-FOXQ1 / FKHRL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FOXQ1 |
|---|---|
| Synonyms | HFH1 |
| Function | Plays a role in hair follicle differentiation. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089}. |
| Tissue Location | Expressed predominantly in the stomach, trachea, bladder and salivary gland. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).
References
FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth. Kaneda H, et al. Cancer Res, 2010 Mar 1. PMID 20145154.
Atrogin-1, MuRF1, and FoXO, as well as phosphorylated GSK-3beta and 4E-BP1 are reduced in skeletal muscle of chronic spinal cord-injured patients. L茅ger B, et al. Muscle Nerve, 2009 Jul. PMID 19533653.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Transforming growth factor-beta 2 is a transcriptional target for Akt/protein kinase B via forkhead transcription factor. Samatar AA, et al. J Biol Chem, 2002 Aug 2. PMID 12011061.
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