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Goat Anti-NEDD1 Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8NHV4 |
| Other Accession | NP_690869, 121441 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 100ug/200ul |
| Isotype | IgG |
| Calculated MW | 71966 Da |
| Gene ID | 121441 |
|---|---|
| Other Names | Protein NEDD1, Neural precursor cell expressed developmentally down-regulated protein 1, NEDD-1, NEDD1 |
| Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-NEDD1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NEDD1 |
|---|---|
| Function | Required for mitosis progression. Promotes the nucleation of microtubules from the spindle. |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor. Crawford NP, et al. J Biol Chem, 2009 Oct 16. PMID 19710015.
Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gammaTuRC to the centrosome. Zhang X, et al. J Cell Sci, 2009 Jul 1. PMID 19509060.
The centrosome protein NEDD1 as a potential pharmacological target to induce cell cycle arrest. Tillement V, et al. Mol Cancer, 2009 Feb 25. PMID 19243593.
FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle. Zhu H, et al. J Cell Biol, 2008 Dec 1. PMID 19029337.
The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation. Petretti C, et al. EMBO Rep, 2006 Apr. PMID 16462731.
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