Goat Anti-NPFFR1 Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q9GZQ6 |
| Other Accession | NP_071429, 64106 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 100ug/200ul |
| Isotype | IgG |
| Calculated MW | 47819 Da |
| Gene ID | 64106 |
|---|---|
| Other Names | Neuropeptide FF receptor 1, G-protein coupled receptor 147, RFamide-related peptide receptor OT7T022, NPFFR1, GPR147, NPFF1 |
| Dilution | WB~~1:1000 E~~N/A |
| Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-NPFFR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NPFFR1 (HGNC:17425) |
|---|---|
| Synonyms | GPR147, NPFF1 |
| Function | Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |

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References
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axis. Ubuka T, et al. PLoS One, 2009 Dec 22. PMID 20027225.
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Grupe A, et al. Am J Hum Genet, 2006 Jan. PMID 16385451.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Hinuma S, et al. Nat Cell Biol, 2000 Oct. PMID 11025660.
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