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Goat Anti-SV2A Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IF, Pep-ELISA |
|---|---|
| Primary Accession | Q7L0J3 |
| Other Accession | NP_055664, 9900, 64051 (mouse), 117559 (rat) |
| Reactivity | Rat |
| Predicted | Human, Mouse, Pig, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 100ug/200ul |
| Isotype | IgG |
| Calculated MW | 82695 Da |
| Gene ID | 9900 |
|---|---|
| Other Names | Synaptic vesicle glycoprotein 2A, SV2A, KIAA0736 |
| Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-SV2A Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SV2A |
|---|---|
| Synonyms | KIAA0736 |
| Function | Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity). |
| Cellular Location | Presynapse {ECO:0000250|UniProtKB:Q9JIS5}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q02563}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q02563}. Note=Enriched in chromaffin granules, not present in adrenal microsomes. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas (By similarity). Colocalizes with ATP2B1 at photoreceptor synaptic terminals. {ECO:0000250|UniProtKB:Q02563, ECO:0000250|UniProtKB:Q9JIS5} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Expression of synaptic vesicle protein 2A in epilepsy-associated brain tumors and in the peritumoral cortex. de Groot M, et al. Neuro Oncol, 2010 Mar. PMID 20167814.
Botulinum toxin type A inhibits the growth of LNCaP human prostate cancer cells in vitro and in vivo. Karsenty G, et al. Prostate, 2009 Aug 1. PMID 19399787.
Expression patterns of synaptic vesicle protein 2A in focal cortical dysplasia and TSC-cortical tubers. Toering ST, et al. Epilepsia, 2009 Jun. PMID 19220410.
No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy. Lynch JM, et al. Epilepsy Res, 2009 Jan. PMID 18977120.
Synaptic vesicle protein 2 binds adenine nucleotides. Yao J, et al. J Biol Chem, 2008 Jul 25. PMID 18524768.
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