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FOXB1 / FKH5 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IF, ICC, E |
|---|---|
| Primary Accession | Q99853 |
| Other Accession | NP_036314.2, 27023, 64290 (mouse) |
| Reactivity | Mouse |
| Predicted | Human, Rat, Pig, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 34978 Da |
| Gene ID | 27023 |
|---|---|
| Other Names | Forkhead box protein B1, Transcription factor FKH-5, FOXB1, FKH5 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FOXB1 / FKH5 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FOXB1 |
|---|---|
| Synonyms | FKH5 |
| Function | Transcription factor expressed by neural progenitor cells in specific regions of the embryonic neuroepithelium. Essential for the mammillary nuclei maintenance. Negatively regulates the proliferation of oligodendrocyte progenitors and promotes oligodendrocyte maturation. Also expressed in mammary glands, plays a role in lactation, controls development of mammary glands and the inferior colliculi of the midbrain in the central nervous system that regulates the milk-ejection reflex. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q64732}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
The winged helix gene, Foxb1, controls development of mammary glands and regions of the CNS that regulate the milk-ejection reflex. Kloetzli JM, Fontaine-Glover IA, Brown ER, Kuo M, Labosky PA. Genesis. 2001 Feb;29(2):60-71. PMID: 11170346
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