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Histamine Receptor H1 (C Term) Antibody (C-Term)

Peptide-affinity purified goat antibody

     
  • IHC - Histamine Receptor H1 (C Term) Antibody (C-Term) AF2455a
    AF2455a (4 µg/ml) staining of paraffin embedded Human Colon. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
    detail
  • IHC - Histamine Receptor H1 (C Term) Antibody (C-Term) AF2455a
    EB06904 (4µg/ml) staining of paraffin embedded Human Colon. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
    detail
  • IHC - Histamine Receptor H1 (C Term) Antibody (C-Term) AF2455a
    EB06904 (5µg/ml) staining of paraffin embedded Human Small Intestine. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
    detail
  • FC - Histamine Receptor H1 (C Term) Antibody (C-Term) AF2455a
    EB06904 Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) fol
    detail
  • FC - Histamine Receptor H1 (C Term) Antibody (C-Term) AF2455a
    EB06904 Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) fol
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC, IF, FC, Pep-ELISA
Primary Accession P35367
Other Accession NP_000852.1, NP_001091681.1, NP_001091682.1, NP_001091683.1, 3269, 15465 (mouse), 24448 (rat)
Reactivity Human
Predicted Mouse, Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 55784 Da
Additional Information
Gene ID 3269
Other Names Histamine H1 receptor, H1R, HH1R, HRH1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHistamine Receptor H1 (C Term) Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HRH1
Function In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations ( 0 )

Background

Variants (NP_000852.1; NP_001091681.1; NP_001091682.1; NP_001091683.1) encode the same protein.

References

Beta(2)-adrenergic receptor-mediated histamine H(1) receptor down-regulation: another possible advantage of beta(2) agonists in asthmatic therapy. Kawakami N, Miyoshi K, Horio S, Fukui H. J Pharmacol Sci. 2004 Apr;94(4):449-58. PMID: 15107586

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$ 341.00
Cat# AF2455a
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