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T-cell differentiation protein Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | P21145 |
| Other Accession | NP_002362.1, NP_071884.1, 4118, 17153 (mouse), 25263 (rat) |
| Predicted | Human, Mouse, Rat |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 16714 Da |
| Gene ID | 4118 |
|---|---|
| Other Names | Myelin and lymphocyte protein, T-lymphocyte maturation-associated protein, MAL |
| Dilution | E~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | T-cell differentiation protein Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MAL |
|---|---|
| Function | May be involved in vesicular trafficking from the Golgi apparatus to the cell membrane. Plays a role in the maintenance of the myelin sheath, and in axon-glia and glia-glia interactions. |
| Cellular Location | Membrane; Multi-pass membrane protein. Cell membrane. Note=Found in lipid rafts {ECO:0000250|UniProtKB:O09198} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognise isoform a (NP_002362.1) and isoform c (NP_071884.1).
References
A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. Khor CC, Chapman SJ, Vannberg FO, Dunne A, Murphy C, Ling EY, Frodsham AJ, Walley AJ, Kyrieleis O, Khan A, Aucan C, Segal S, Moore CE, Knox K, Campbell SJ, Lienhardt C, Scott A, Aaby P, Sow OY, Grignani RT, Sillah J, Sirugo G, Peshu N, Williams TN, Maitla Nat Genet. 2007 Apr;39(4):523-528. Epub 2007 Feb 25. PMID: 17322885
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