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TREX2 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC, E |
|---|---|
| Primary Accession | Q9BQ50 |
| Other Accession | NP_542432.2, 11219 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 25922 Da |
| Gene ID | 11219 |
|---|---|
| Other Names | Three prime repair exonuclease 2, 3.1.11.2, 3'-5' exonuclease TREX2, TREX2 |
| Dilution | IHC~~1:100~500 E~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TREX2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TREX2 |
|---|---|
| Function | Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair. |
| Cellular Location | Nucleus. |
| Tissue Location | Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partnering. de Silva U, Choudhury S, Bailey SL, Harvey S, Perrino FW, Hollis T. J Biol Chem. 2007 Apr;282(14):10537-43. Epub 2007 Feb 9. PMID: 17293595
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