MSH4 (internal) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| E |
---|---|
Primary Accession | O15457 |
Other Accession | NP_002431.2, 4438, 55993 (mouse) |
Predicted | Human, Mouse |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 104756 Da |
Gene ID | 4438 |
---|---|
Other Names | MutS protein homolog 4, hMSH4, MSH4 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MSH4 (internal) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MSH4 |
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Function | Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis. |
Cellular Location | Chromosome {ECO:0000250|UniProtKB:Q99MT2}. |
Tissue Location | Highly expressed in testis (PubMed:33437391, PubMed:9299235). Also expressed in the ovary (PubMed:9299235) |

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Provided below are standard protocols that you may find useful for product applications.
References
CRM1-dependent nuclear export and dimerization with hMSH5 contribute to the regulation of hMSH4 subcellular localization. Neyton S, Lespinasse F, Lahaye F, Staccini P, Paquis-Flucklinger V, Santucci-Darmanin S. Exp Cell Res. 2007 Oct 15;313(17):3680-93. Epub 2007 Aug 21. PMID: 17869244

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