TACR2 / Neurokinin 2 receptor Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | P21452 |
Other Accession | NP_001048.2, 6865 |
Predicted | Human, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 44442 Da |
Gene ID | 6865 |
---|---|
Other Names | Substance-K receptor, SKR, NK-2 receptor, NK-2R, Neurokinin A receptor, Tachykinin receptor 2, TACR2, NK2R, NKNAR, TAC2R |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TACR2 / Neurokinin 2 receptor Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TACR2 |
---|---|
Synonyms | NK2R, NKNAR, TAC2R |
Function | This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
References
Increased neurokinin-2 receptor expression in alveolar macrophages of smokers with COPD. Miotto D, Boschetto P, Cavallesco G, Zeni E, Querzoli P, Pedriali M, Chiarelli S, Fabbri LM, Mapp CE. Histopathology. 2007 Jul;51(1):128-31. Epub 2007 May 26. No abstract available. PMID: 17532769
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