Neurexin 3 / NRXN3 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | Q9Y4C0 |
Other Accession | NP_004787.2, 9369, 18191 (mouse) |
Predicted | Human, Mouse, Pig, Dog |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 180599 Da |
Gene ID | 9369 |
---|---|
Other Names | Neurexin-3, Neurexin III-alpha, Neurexin-3-alpha, NRXN3, C14orf60, KIAA0743 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Neurexin 3 / NRXN3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NRXN3 |
---|---|
Synonyms | C14orf60, KIAA0743 |
Function | Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling (By similarity). |
Cellular Location | Presynaptic cell membrane {ECO:0000250|UniProtKB:Q9CS84}; Single-pass type I membrane protein |
Tissue Location | Expressed in the blood vessel walls (at protein level). Highly expressed in brain, lung, and pancreas; a lower level of expression is detectable in heart, placenta, liver, and kidney, whereas no expression can be observed in skeletal muscle. Isoform 4a is heart- specific. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize the reported isoform 1 (NP_004787.2).
References
Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.
susceptibility genes for clefts. Vieira AR, McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML. Genet Med. 2008 Sep;10(9):668-74. PMID: 18978678
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