Desmoglein 1 / DSG1 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC, E |
---|---|
Primary Accession | Q02413 |
Other Accession | NP_001933.2, 1828 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 113748 Da |
Gene ID | 1828 |
---|---|
Other Names | Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, DG1, DGI, Pemphigus foliaceus antigen, DSG1, CDHF4 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Desmoglein 1 / DSG1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DSG1 |
---|---|
Synonyms | CDHF4 |
Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q7TSF1}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q7TSF1} Cell junction, desmosome. Cytoplasm. Nucleus |
Tissue Location | Epidermis, tongue, tonsil and esophagus. |
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Provided below are standard protocols that you may find useful for product applications.
References
Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome Nilles L.A., Parry D.A., Powers E.E., Angst B.D., Wagner R.M., Green K.J J. Cell Sci. 1991 Aug 99 ( Pt 4): 809-21 PMID: 1770008
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