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PON2 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q15165 |
| Other Accession | NP_000296.2, NP_001018171.1, 5445, 296851 (rat) |
| Reactivity | Human |
| Predicted | Rat, Pig, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 39381 Da |
| Gene ID | 5445 |
|---|---|
| Other Names | Serum paraoxonase/arylesterase 2, PON 2, 3.1.1.2, 3.1.1.81, Aromatic esterase 2, A-esterase 2, Serum aryldialkylphosphatase 2, PON2 |
| Dilution | WB~~1:1000 E~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PON2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PON2 |
|---|---|
| Function | Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis. |
| Cellular Location | Membrane; Peripheral membrane protein |
| Tissue Location | Widely expressed with highest expression in liver, lung, placenta, testis and heart. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize isoforms 1 and 2 (NP_000296.2; NP_001018171.1).
References
Paraoxonase gene polymorphism in south-western Korean population. Shin BS. Journal of Korean medical science 2009 Aug 24 (4): 561-6. PMID: 19654933
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