HOXA1 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P49639 |
Other Accession | NP_005513.1, NP_705873.2, 3198, 15394 (mouse), 25607 (rat) |
Reactivity | Human |
Predicted | Mouse, Rat, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 36641 Da |
Gene ID | 3198 |
---|---|
Other Names | Homeobox protein Hox-A1, Homeobox protein Hox-1F, HOXA1, HOX1F |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HOXA1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HOXA1 |
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Synonyms | HOX1F |
Function | Sequence-specific transcription factor (By similarity). Regulates multiple developmental processes including brainstem, inner and outer ear, abducens nerve and cardiovascular development and morphogenesis as well as cognition and behavior (PubMed:16155570). Also part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Seems to act in the maintenance and/or generation of hindbrain segments (By similarity). Activates transcription in the presence of PBX1A and PKNOX1 (By similarity). |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:P09022}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize reported isoforms a and b (NP_005513.1; NP_705873.2).
References
Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome. Chakrabarti B, Dudbridge F, Kent L, Wheelwright S, Hill-Cawthorne G, Allison C, Banerjee-Basu S, Baron-Cohen S, Autism research : official journal of the International Society for Autism Research 2009 Jun 2 (3): 157-77. PMID: 19598235
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