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CETP Antibody (N-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, Pep-ELISA |
|---|---|
| Primary Accession | P11597 |
| Other Accession | NP_000069.2, 1071 |
| Predicted | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 54756 Da |
| Gene ID | 1071 |
|---|---|
| Other Names | Cholesteryl ester transfer protein, Lipid transfer protein I {ECO:0000312|MIM:118470}, CETP (HGNC:1869) |
| Dilution | WB~~1:1000 IF~~1:50~200 Pep-ELISA~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CETP Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CETP (HGNC:1869) |
|---|---|
| Function | Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL (PubMed:24293641, PubMed:3281933, PubMed:3600759). Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (PubMed:17237796). |
| Cellular Location | Secreted. Note=Secreted in plasma |
| Tissue Location | Expressed by the liver and secreted in plasma. |
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Provided below are standard protocols that you may find useful for product applications.
References
Association of circulating cholesteryl ester transfer protein activity with incidence of cardiovascular disease in the community. Vasan RS, Pencina MJ, Robins SJ, Zachariah JP, Kaur G, D'Agostino RB, Ordovas JM, Circulation 2009 Dec 120 (24): 2414-20. PMID: 19948972
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